https://phlox.or.id/index.php/sjped <p><strong>Scientific Journal of Pediatrics (SJPed) </strong>is an international, peer-review, and open access journal dedicated to pediatrics. <strong>SJPed</strong> publishes twice a year. The journal publishes all type of original articles, case reports, review articles, narrative review, meta-analysis, systematic review, mini-reviews and book review. <strong>SJPed</strong>&nbsp;is an official journal of <a href="https://institute.phlox.or.id/" target="_blank" rel="noopener">Phlox Institute: Indonesian Medical Research Organization</a>. SJPed has eISSN:&nbsp;<a href="https://issn.brin.go.id/terbit/detail/20230909521186500" target="_blank" rel="noopener">3025-6224</a>.</p> <p style="text-align: center;"><a href="https://issn.brin.go.id/terbit/detail/20230909521186500" target="_blank" rel="noopener"><img src="/public/site/images/erik_normann/dok_sk_2023_09_BARCODE_3025622400.png" width="183" height="80"></a></p> <p style="text-align: center;">&nbsp;</p> Phlox Institute: Indonesian Medical Research Organization en-US Scientific Journal of Pediatrics 3025-6224 <p><strong>Scientific Journal of Pediatrics (SJPed) </strong>allow the author(s) to hold the copyright without restrictions and&nbsp; allow the author(s) to retain publishing rights without restrictions, also the owner of the commercial rights to the article&nbsp; is&nbsp; the author.</p> https://phlox.or.id/index.php/sjped/article/view/166 <p><strong>Introduction: </strong>Surfactant deficiency is a major contributor to neonatal respiratory distress syndrome (RDS) in preterm infants. Surfactant replacement therapy has become a cornerstone in managing RDS, but its impact on broader respiratory and hemodynamic outcomes remains an area of active investigation. This meta-analysis aimed to comprehensively evaluate the effects of surfactant therapy on preterm neonates, encompassing both respiratory and hemodynamic parameters.</p> <p><strong>Methods:</strong> A systematic search of electronic databases (PubMed, Embase, Cochrane Library) was conducted to identify randomized controlled trials (RCTs) and observational studies evaluating surfactant therapy in preterm neonates. Studies reporting on respiratory outcomes (need for mechanical ventilation, duration of ventilation, oxygen requirement) and hemodynamic outcomes (patent ductus arteriosus (PDA) incidence, blood pressure, cerebral blood flow) were included. Data extraction and quality assessment were performed independently by two reviewers. Meta-analyses were conducted using random-effects models.</p> <p><strong>Results:</strong> A total of 35 studies (22 RCTs, 13 observational studies) involving 4,875 preterm neonates were included. Surfactant therapy was associated with a significant reduction in the need for mechanical ventilation (RR 0.72, 95% CI 0.65-0.80, p&lt;0.001), duration of mechanical ventilation (MD -1.8 days, 95% CI -2.5 to -1.1, p&lt;0.001), and oxygen requirement (MD -5%, 95% CI -7 to -3, p&lt;0.001). A trend towards reduced incidence of PDA was observed (RR 0.85, 95% CI 0.71-1.02, p=0.08). Surfactant therapy also led to improvements in blood pressure parameters and cerebral blood flow.</p> <p><strong>Conclusion:</strong> Surfactant therapy in preterm neonates confers significant benefits in respiratory outcomes, including reduced need for and duration of mechanical ventilation, and decreased oxygen requirement. A potential beneficial effect on PDA incidence warrants further investigation. These findings underscore the critical role of surfactant therapy in improving the respiratory and hemodynamic status of preterm neonates.</p> Ni Luh Ayudimartini Copyright (c) 2024-09-19 2024-09-19 2 2 159 170 10.59345/sjped.v2i2.166 https://phlox.or.id/index.php/sjped/article/view/172 <p><strong>Introduction: </strong>Soil-transmitted helminths (STHs) are a major public health concern, especially in remote indigenous communities with limited access to clean water and sanitation. This study aimed to investigate the influence of personal hygiene practices on the prevalence of STH infections in children in the Ammatoa Kajang community of Bulukumba Regency, Indonesia.</p> <p><strong>Methods: </strong>An observational case series was conducted among children aged 3-13 years in the Ammatoa Kajang community. Data on personal hygiene practices were collected through questionnaires and interviews, while stool samples were examined for STH infections using the Kato-Katz method. Data were analyzed using correlation tests to determine the relationship between personal hygiene and STH prevalence.</p> <p><strong>Results:</strong> The prevalence of STH infection was 45%, with <em>Ascaris lumbricoides</em> being the most common (30%), followed by <em>Trichuris trichiura </em>(10%) and hookworm (5%). Poor personal hygiene practices, such as infrequent handwashing, not using soap after defecation, and not wearing footwear, were significantly associated with an increased risk of STH infection.</p> <p><strong>Conclusion: </strong>Personal hygiene plays a crucial role in the prevalence of STH infections among children in the Ammatoa Kajang community. Health promotion programs focused on improving personal hygiene practices, along with improved sanitation facilities, are essential for reducing the burden of STH infections in this remote indigenous community.</p> Nur Laela Alydrus Ka’bah Rugayyah Alyidrus Risky Nurul Fadlila RN Fika Andriani Copyright (c) 2025-01-09 2025-01-09 2 2 171 183 10.59345/sjped.v2i2.172